Characterization of viral transcriptomes such as viruses with complex genomes
Identification and characterization of fusion gene transcripts in cancer cells
Disease diagnosis, prognosis and therapeutic selection
Studies of alternative splicing events for complete understanding of gene transcription and associated diseases (e.g, neurological diseases)
Cell fate and differential expression studies
We can perform long-read RNA sequencing and use the data for genome annotation.
We can perform RNA-seq and downstream analysis to determine gene expression changes in cell fate studies or other applications.
Considering RNA-sequencing for your research? Get in touch to discuss your research objectives.
Long-read sequencing improves alternative splicing detection by capturing entire transcripts within single reads, and can be used to resolve the complex gene structure through the direct observation of underlying exon combinations.
Nanopore technology has been used as a tool for investigating changes in splicing in cancer-associated mutations.
Nanopore technology has been used as a tool for investigating cancer-associated gene mutations that cause alternative splicing.
RNA reads are generated while avoiding the PCR amplification biases, generating sequence analysis with base alterations and polyadenylation.
If you have any inquiries get in touch with us and we'll get back to you right away.